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KMID : 0357419930230010079
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Korean journal of Virology
1993 Volume.23 No. 1 p.79 ~ p.84
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박호선
황규제/전복환/김혜숙/박송용
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Abstract
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Hantaan virus(ROK-84-105) was propagated on various normal human diploid cell lines and guinea pig embryonic lung(GEL) cells. Viral antigens were detected by immunofluorescence assay in each cell lines and immunoblotting pattern of viral
proteins
in
these cells was identical with that of in Vero E6 cells. So, we found that Hantaan virus was succeptible to not only Vero E6 cells and A549 cell but also normal human diploid cell lines and GEL cells, Contiuous propagation of Hantaan virus in
human
diploid cell lines and GEL cells was possible and yield of the virus in human embryonic lung fibroblast(LuMA) was enough to make a vaccine.
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KEYWORD
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